“圣诞浆果”提取物有助于治疗恶性癌症

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“圣诞浆果”提取物有助于治疗恶性癌症

Uvealmelanomaisthemostcommonintraoculartumorinadultsandoftenmetastasizestotheliver,,GαqandGα11,areobservedinapproximately93%αq/11targetshasbeenunsuccessfulintreatinguvealmelanoma,wehavefoundthattheGαq/11inhibitor,FR900359(FR),effectivelyinhibitsoncogenicGαq/11signalinginuvealmelanomacellsexpressingeithermutantGαqorGααq/,colonyformationispreventedbyFRtreatmentofuvealmelanomacellsin3D-cellculture,αq/:OncogenicGαq/11inhibitionbyFR900359maybeapotentialtreatmentoptionforthosewithuvealmelanoma.。